US equity futures were edging lower pre-bell Wednesday as traders look forward to the release of minutes from the Federal Reserve's September policy meeting.

Dow Jones Industrial Average futures were 0.8% lower, S&P 500 futures were down 0.5%, and Nasdaq futures were 0.8% lower.

Traders await the 2 pm ET release of minutes of the Federal Reserve Sept. 16-17 policy session, in which central bankers voted 12-0 to lift interest rates, for insights on the central bank's thinking.

US Secretary of State Marco Rubio said that Iran has missed "multiple" opportunities to reach a deal on its controversial nuclear program, amid the lack of progress in the peace talks between the two nations, CNBC reported. Despite the recent increase in crude exports passing through the Strait of Hormuz, Iran has ramped up attacks on vessels transiting the waterway, with almost 20 ships coming under attack over the past month, the news outlet reported Tuesday.

Traders also digested the latest round of earnings, with Constellation Brands (STZ) posting late Tuesday higher adjusted earnings and net sales for fiscal Q2.

Oil prices were higher, with front-month global benchmark North Sea Brent crude up 0.8% at $101.33 per barrel and US West Texas Intermediate crude 0.4% higher at $89.90 per barrel.

The August consumer credit release is slated for a 3 pm ET release.