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Bicycle Therapeutics Limited

3.81

+0.08002.14%

Volume:337.68K

Turnover:1.26M

Market Cap:265.98M

PE:-1.39

High:3.81

Open:3.71

Low:3.62

Close:3.73

52wk High:9.16

52wk Low:3.33

Shares:69.81M

Float Shares:3.08M

Volume Ratio:0.42

T/O Rate:10.97%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-2.7382

EPS(LYR):-3.1605

ROE:-32.30%

ROA:-17.91%

PB:0.52

PE(LYR):-1.21

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Overview Company News Filings

Analysts Offer Insights on Healthcare Companies: Bicycle Therapeutics (BCYC), Alnylam Pharma (ALNY) and Fortrea Holdings Inc. (FTRE)

Anavex Life Sciences Q2 Net Loss Narrows on Lower R&D Costs

Bicycle Therapeutics Posts Investor Presentation Highlighting Bicycle Molecule Platform and Oncology Pipeline

Bicycle Therapeutics Q2 FY26 Net Loss Narrows to $50.3 Million; R&D Expenses Drop 42% to $41.2 Million

Bicycle Therapeutics Reports Recent Business Progress and Second Quarter 2026 Financial Results

THOMSON REUTERS

Bicycle Therapeutics Q2 Basic EPS USD -0.72

THOMSON REUTERS

Bicycle Therapeutics Q2 Net Income USD -50.333 Million

THOMSON REUTERS

Bicycle Therapeutics COO Jennifer Scott Perry Disposes of USD 6,036.55 in Shares

Bicycle Therapeutics shareholders backed AGM proposals in vote

European Equities Traded in the US as American Depositary Receipts Rise in Wednesday Trading

MT Newswires Live

Bicycle Therapeutics posts corporate presentation outlining Bicycle molecule platform and oncology pipeline

European Equities Traded in the US as American Depositary Receipts Edge Higher in Friday Trading

MT Newswires Live

Bicycle Therapeutics reports initial Duravelo-2 Phase 2 data in metastatic urothelial cancer

Morgan Stanley Sticks to Its Hold Rating for Bicycle Therapeutics (BCYC)

European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading; Gain 1.3% for Week

MT Newswires Live

Bicycle Therapeutics PLC reports results for the quarter ended March 31 - Earnings Summary

Analysts Offer Insights on Healthcare Companies: Bicycle Therapeutics (BCYC) and Option Care Health (OPCH)

European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading

MT Newswires Live

Bicycle Therapeutics Q1 FY26 net loss holds at USD 60.8 million; revenue drops to USD 0.9 million

Bicycle Therapeutics Q1 Pretax Profit USD -60.653 Million

THOMSON REUTERS

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19:00","pubTimestamp":1785409201,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260730:nPLXLCP9ZL:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2649393007","title":"Bicycle Therapeutics COO Jennifer Scott Perry Disposes of USD 6,036.55 in 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USD 6,036.55 in Shares","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644083292","title":"Bicycle Therapeutics shareholders backed AGM proposals in vote","url":"https://stock-news.laohu8.com/highlight/detail?id=2644083292","media":"Reuters","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644083292?lang=en_us&edition=fundamental","pubTime":"2026-06-18 20:21","pubTimestamp":1781785314,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics held its annual shareholder meeting on June 17, 2026.Shareholders backed the return of Felix Baker, along with Hervé Hoppenot, to the board.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate this news brief via EDGAR, the Electronic Data Gathering, Analysis, and Retrieval system operated by the U.S. Securities and Exchange Commission , on June 18, 2026, and is solely responsible for the information contained therein.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260618:nNDL7qBnjg:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2644747343","title":"European Equities Traded in the US as American Depositary Receipts Rise in Wednesday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2644747343","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2644747343?lang=en_us&edition=fundamental","pubTime":"2026-06-17 23:10","pubTimestamp":1781709044,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were sharply higher late Wednesday morning, rising 1.28% to 1,926.15 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by lenders Banco Santander  and Banco Bilbao Vizcaya Argentaria , which advanced 2.5% and 2.3% respectively. They were followed by biopharmaceutical firm argenx  and biotech firm BioNTech , which rose 2.1% and 2% respectively.The decliners from continental Europe were led by pharmaceutical company Sanofi  and telecommunications company Nokia , which dropped 2% and 1.4% respectively. They were followed by software firm SAP  and telecommunications company Ericsson , which were off 1% and 0.8% respectively.The gainers from the UK were led by Mereo BioPharma Group  and lender Barclays , which rose 9% and 3.6% respectively. They were followed by Akari Therapeutics  and Bicycle Therapeutics , which advanced 3.3% and 2.7% respectively.The decliners from the UK and Ireland were le","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BBVA","BNTX","BK4132","BTI","MREO","BK4547","BK4548","BK4551","IE00BFTCPJ56.SGD","IEUR","SNY","LU0889565916.HKD","LU1829250122.USD","BK4020","BP","SAN.AU","LU0300736062.USD","AFG","BK4554","BK4023","VOD","IE00BJJMRZ35.SGD","BTI.AU","BK4591","SAP","ARGX","BCS","SHEL","BK4613","BK4007","BK4585","ERIC","BK4075","BK4568","BPH","IE0002141913.USD","NOK","LNOK","AKTX","IE0009355771.USD","LU2543165471.USD","SHEH","BK4515","EPV","BCYC","LU0109394709.USD","BK4528","BK4107","SAN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2640564957","title":"Bicycle Therapeutics posts corporate presentation outlining Bicycle molecule platform and oncology pipeline","url":"https://stock-news.laohu8.com/highlight/detail?id=2640564957","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2640564957?lang=en_us&edition=fundamental","pubTime":"2026-06-01 21:56","pubTimestamp":1780322172,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics outlined an oncology-focused pipeline built on its Bicycle molecule platform, aiming to deliver payloads to hard-to-drug targets.Lead program nuzefatide pevedotin, an EphA2-targeting Bicycle drug conjugate, is in a Phase 2 open-label trial in second-line or later pancreatic cancer.Presentation highlighted safety data in 161 exposed patients, citing no hemorrhage events to date and no Grade 3 peripheral neuropathy reported.Cash and cash equivalents totaled USD 559.5 million as of March 31, 2026, with expected financial runway into 2030.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate this news brief on June 01, 2026, and is solely responsible fo","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260601:nNDL289kMR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637080348","title":"European Equities Traded in the US as American Depositary Receipts Edge Higher in Friday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2637080348","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637080348?lang=en_us&edition=fundamental","pubTime":"2026-05-22 23:06","pubTimestamp":1779462387,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were trending slightly higher late Friday morning, edging up 0.11% to 1,880.31 on the S&P Europe Select ADR Index, which has surged 3","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4521","IE00BMPRXR70.SGD","SAN.AU","BK4547","BK4591","PUK","GRFS","BK4141","BK4554","BBVA","NOK","BK4207","BK4007","TRIB","E","ERIC","BK4095","IE00BMPRXN33.USD","AKTX","SAN","BCYC","SLN","AUTL","AFG","BK4201","BK4082","IEUR","BDRX","BK4505","NTZ","SQNS","BK4139","BK4117","BK4162","BK4107","BK7142","MREO","BK4020","EPV","LNOK","BK4515"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2637352795","title":"Bicycle Therapeutics reports initial Duravelo-2 Phase 2 data in metastatic urothelial cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2637352795","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2637352795?lang=en_us&edition=fundamental","pubTime":"2026-05-22 05:00","pubTimestamp":1779397235,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics flagged initial data from its randomized Phase 2 Duravelo-2 trial of Nectin-4 drug conjugate zelenectide pevedotin in metastatic urothelial cancer, with results set for presentation at the 2026 ASCO Annual Meeting.The dose-optimized regimen in combination with Merck’s Keytruda produced responses broadly in line with published first-line standards of care, supporting continued development in an increasingly competitive setting.The company highlighted a potentially differentiated tolerability profile versus published standard-of-care benchmarks, with fewer treatment-limiting side effects such as skin toxicity and peripheral neuropathy.Updated Phase 1 Duravelo-1 findings will also be presented at ASCO, pointing to clinically meaningful disease control and progression outcomes in cisplatin-ineligible patients treated with the combination.Additional results from the randomized Phase 2 program are expected in 2H 2026, a key catalyst for next-step partnering and registrat","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260521:nNDL9Z7jVB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BCYC","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2636349076","title":"Morgan Stanley Sticks to Its Hold Rating for Bicycle Therapeutics (BCYC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2636349076","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2636349076?lang=en_us&edition=fundamental","pubTime":"2026-05-18 20:59","pubTimestamp":1779109181,"startTime":"0","endTime":"0","summary":"Morgan Stanley analyst Maxwell Skor maintained a Hold rating on Bicycle Therapeutics today and set a price target of $4.45. Skor covers the Healthc...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/morgan-stanley-sticks-to-its-hold-rating-for-bicycle-therapeutics-bcyc-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/morgan-stanley-sticks-to-its-hold-rating-for-bicycle-therapeutics-bcyc-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632643568","title":"European Equities Traded in the US as American Depositary Receipts Flat in Friday Trading; Gain 1.3% for Week","url":"https://stock-news.laohu8.com/highlight/detail?id=2632643568","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632643568?lang=en_us&edition=fundamental","pubTime":"2026-05-01 23:10","pubTimestamp":1777648259,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts were trending marginally higher late Friday morning, rising 0.05% to 1,824.45 on the S&P Europe Select ADR Index, which is up 1.25% f","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["NTZ","IE00BZ1G4Q59.USD","PXJ","DBVT","BK4183","LU0300736492.USD","BCYC","BK4592","NVOX","UL","BK4585","IEO","GUSH","BK4535","BK4547","ERX","LU0098860793.USD","AMRN","USE","DBC","LU1162221912.USD","LU1093756168.USD","DBE","DRLL","IE00BMPRXR70.SGD","IE00BMPRXN33.USD","BK4095","BK4007","DIG","BK4020","PSO","EQNR","LU0072461881.USD","VDE","BK4204","UN","IE00BKVL7J92.USD","SHEH","ULVR.UK","LU0162691827.USD","BP","LU1829250122.USD","BK4142","BK4139","BDRX","NVO","BPH","BNTX","SHEL","BK4107","AKTX","LU0278409577.USD","LU0320765646.SGD","LU0124676726.USD","BK7104","BK4532","BK4117","NVOH","NOK","CLLS","BK4111","LU0006061336.USD","LU2236285917.USD","DRIP","LNOK","IXC","LU0300736062.USD","BK4551","CUK","BK4599","BK4588","BK4568","BK4548","LU0689626769.HKD","LU0154236417.USD","LU1093756325.SGD","BK4201"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632191886","title":"Bicycle Therapeutics PLC reports results for the quarter ended March 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2632191886","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632191886?lang=en_us&edition=fundamental","pubTime":"2026-05-01 19:07","pubTimestamp":1777633623,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics PLC reports results for the quarter ended March 31 - Earnings SummaryBicycle Therapeutics PLC BCYC.OQ reported a quarterly adjusted loss of 87 cents per share for the quarter ende","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260501:nL8N41E0LD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632650170","title":"Analysts Offer Insights on Healthcare Companies: Bicycle Therapeutics (BCYC) and Option Care Health (OPCH)","url":"https://stock-news.laohu8.com/highlight/detail?id=2632650170","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632650170?lang=en_us&edition=fundamental","pubTime":"2026-05-01 02:20","pubTimestamp":1777573209,"startTime":"0","endTime":"0","summary":"There’s a lot to be optimistic about in the Healthcare sector as 2 analysts just weighed in on Bicycle Therapeutics (BCYC) and Option Care Health (...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-bicycle-therapeutics-bcyc-and-option-care-health-opch-blurbs-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/analysts-offer-insights-on-healthcare-companies-bicycle-therapeutics-bcyc-and-option-care-health-opch-blurbs-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["HCSG","BK4585","BK4588","BK4139","LU0106261612.USD","OPCH","XBI","LU2065731478.USD","LU0012050646.USD","XLV","BK4196","LU0029874061.USD","LABU","BK4581","LU0128526141.USD","BCYC","BK4137"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2632652327","title":"European Equities Traded in the US as American Depositary Receipts Rise in Thursday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2632652327","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2632652327?lang=en_us&edition=fundamental","pubTime":"2026-04-30 23:06","pubTimestamp":1777561599,"startTime":"0","endTime":"0","summary":"European equities traded in the US as American depositary receipts rose late Thursday morning, gaining 2.20% to 1,818.51 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by pharmaceutical company Novo Nordisk  and lender ING Groep , which advanced 5.3% and 4.9% respectively. They were followed by biopharmaceutical firm Grifols  and consumer goods firm Unilever , which rose 3.2% and 3.1% respectively.The decliners from continental Europe were led by internet advertising firm Criteo  and telecommunications company Nokia , which fell 3.2% and 1.9% respectively.The gainers from the UK were led by cruise line operator Carnival  and utilities company National Grid , which rose 4.8% and 3.5% respectively. They were followed by Lloyds Banking Group  and telecommunications operator Vodafone Group , which were up 2.6% and 2.3% respectively.The decliners from the UK and Ireland were led by software firm Endava  and Bicycle Therapeutics , which lost 5.2% and 2.3% re","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IE00BKVL7J92.USD","BK4139","ULVR.UK","NVOH","AMRN","IE00BZ1G4Q59.USD","BK4183","BK4585","LNOK","IE00BFMHRM44.USD","LU0084288595.USD","BK4532","LU1093756325.SGD","BK4207","NOK","BK4020","UN","BK4208","NVOX","BK4117","BK4547","BK4009","LU0648005311.SGD","LU0689626769.HKD","BK7104","DAVA","BK4107","ING","CRTO","BK4588","NGG","BK4599","BK7141","GRFS","UL","BK4134","BK7505","BK4007","BCYC","NVO","BK4132","IE00BMPRXN33.USD","LU0124676726.USD","CUK","MREO","BK4592","VOD","BK4521","IE00BMPRXR70.SGD","LU0154236417.USD","BK4505","BK4142","LYG","LU1093756168.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631563559","title":"Bicycle Therapeutics Q1 FY26 net loss holds at USD 60.8 million; revenue drops to USD 0.9 million","url":"https://stock-news.laohu8.com/highlight/detail?id=2631563559","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631563559?lang=en_us&edition=fundamental","pubTime":"2026-04-30 19:01","pubTimestamp":1777546877,"startTime":"0","endTime":"0","summary":"Bicycle Therapeutics posted a Q1 net loss of 60.8 million, or $ per share.Operating loss narrowed to 65.5 million on lower R&D and G&A costs.Cash and cash equivalents declined to 559.5 million as of March 31, 2026.Pipeline update highlighted first patient dosed in Phase 2 PDAC trial of nuzefatide pevedotin; preferred dose set at 8 mg/m2 Q2W.Strategic reprioritization included converting Duravelo-2 into a randomized Phase 2 trial, shutting enrollment for Duravelo-3 and Duravelo-4, and cutting workforce about 30%.Management said actions should cut annual operating expenses about 50% and extend cash runway into 2030.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Bicycle Therapeutics plc published the original content used to generate thi","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nNDL9cKpXk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2631330646","title":"Bicycle Therapeutics Q1 Pretax Profit USD -60.653 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2631330646","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2631330646?lang=en_us&edition=fundamental","pubTime":"2026-04-30 19:00","pubTimestamp":1777546801,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260430:nPLXD4F1A3:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BCYC"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":2,"totalSize":48,"code":"91000000","status":"200"}]}}