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The Swiss pharma group said Monday that it plans new studies for its breast-cancer drug candidate giredestrant across different treatment lines, combinations and settings of the disease. \"While the breadth of the giredestrant program and broader pipeline provided encouragement around Roche's longer-term growth potential, the lack of midterm guidance update meant the event unlikely provided the incremental upside catalyst some investors had been hoping for,\" they add. Shares fall 1.2%.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["HRTS","03165","CANC","BK4007","RHHBY"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2671925214","title":"Roche Needs Next Drug Launches to Go Smoothly","url":"https://stock-news.laohu8.com/highlight/detail?id=2671925214","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2671925214?lang=en_us&edition=fundamental","pubTime":"2026-09-29 20:35","pubTimestamp":1790685300,"startTime":"0","endTime":"0","summary":"1235 GMT - Roche Holding shares trade at a premium to those of peers, which will be difficult to justify if the launches of its next drugs don't deliver on expectations, Jefferies analysts say in a research note. There were no big surprises in the Swiss drugmaker's update on its pharma business held Monday and 2027 is shaping up to be a year more focused on regulatory filings than on clinical-trial results, the analysts say. \"What is now perhaps even clearer is that 2027 giredestrant and fenebrutinib launches must deliver, if approved, as key clinical catalysts don't emerge until closer to 2028,\" Jefferies says, referring to Roche's new drugs for breast cancer and multiple sclerosis, respectively. Shares fall 1.2%.","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RHHBY","BK4007","03165","CANC","HRTS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2671214345","title":"Roche Signals it is Too Soon to Know if AI Improves Trial Success Rates","url":"https://stock-news.laohu8.com/highlight/detail?id=2671214345","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2671214345?lang=en_us&edition=fundamental","pubTime":"2026-09-29 20:22","pubTimestamp":1790684520,"startTime":"0","endTime":"0","summary":"1222 GMT - Roche Holding's research and early development is becoming more productive thanks to the integration of AI into its workflows, but it is too soon to know if the technology improves a drug candidate's chances in a clinical trial, J.P. Morgan analysts say in a research note. The Swiss drugmaker said it is using AI to speed up the process of discovering new medicines, and ultimately aims to improve the quality of those that it moves to the development phase. \"While they are making significant progress enhancing the research process, whether this will lead to enhanced probability of success will only become clear as the molecules go through clinical testing over the coming 3-5 years,\" the analysts say. Shares fall 1.4%.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AIPO","CHAT","HRTS","03165","QTOC","RHHBY","ARTY","BK4007","CANC","VTHR","AGIX"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2671112292","title":"Roche Seems Increasingly Confident in Obesity Portfolio","url":"https://stock-news.laohu8.com/highlight/detail?id=2671112292","media":"Dow Jones","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2671112292?lang=en_us&edition=fundamental","pubTime":"2026-09-29 20:13","pubTimestamp":1790683980,"startTime":"0","endTime":"0","summary":"1212 GMT - Roche Holding's confidence in its portfolio of medicines for obesity and diabetes seems to be growing as the Swiss drugmaker seeks an expansion into broader cardiovascular indications, UBS analysts say in a research note. \"Management continues to expect a highly segmented obesity market, with orals a critical pillar both as monotherapy and in combinations, and sees oral therapies expanding the market,\" the analysts say. Roche believes the glucose-control performance of its enicepatide drug candidate in a recent midstage trial warrants a head-to-head comparison study against Eli Lilly's Mounjaro in diabetes, with no decision yet on a similar study in obesity, they add. Moreover, the company plans to test enicepatide for cardiac conditions, while moving two other experimental obesity drugs to late-stage studies. Shares fall 1.1%.","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Roche Seems Increasingly Confident in Obesity Portfolio","news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RHHBY","BK4007","03165","CANC","HRTS"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2671211626","title":"Eli Lilly Reports Zepbound Showed 4.5% Greater Weight Loss Than Novo Nordisk's Wegovy HD","url":"https://stock-news.laohu8.com/highlight/detail?id=2671211626","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2671211626?lang=en_us&edition=fundamental","pubTime":"2026-09-29 20:02","pubTimestamp":1790683358,"startTime":"0","endTime":"0","summary":"Eli Lilly  said Tuesday that a new indirect analysis showed its drug Zepbound produced 4.5% greater weight loss than Novo Nordisk's  Wegovy HD in adults with obesity.The analysis compared data from the SURMOUNT-1 and STEP UP trials, according to the company.Patients taking a 15-milligram dose of Zepbound achieved the 4.5% greater average weight reduction over 72 weeks, the company said.Participants receiving a 10-milligram dose of the medication lost 3.2% more of their body weight on average compared with those on Wegovy HD, it said.Those taking the highest Zepbound dose were more than three times as likely to achieve at least a 20% reduction in body weight, and discontinuation rates due to adverse events were comparable across both treatments, Eli Lilly 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Cyprumed said the deal entitles it to upfront and milestone payments of up to $493 million.No other trial details were disclosed. Cyprumed said the trial triggers a payment under the agreement with Merck, without disclosing the specific 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