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Therapeutics Says Phase 2 Major Depressive Disorder Study Fails to Meet Primary Efficacy Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2667695720","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667695720?lang=en_us&edition=fundamental","pubTime":"2026-09-15 04:52","pubTimestamp":1789419160,"startTime":"0","endTime":"0","summary":"Contineum Therapeutics  said late Monday the phase 2 MOONLIGHT-1 trial of JNJ-5120/PIPE-307 for the treatment of major depressive disorder did not meet its primary efficacy endpoint.JNJ-5120/PIPE-307 is being developed by Johnson & Johnson  under a global license and development agreement, the company noted.The study evaluated improvement from baseline in the Montgomery-Asberg Depression Rating Scale total score at Day 5 compared with placebo, the company said, adding that the treatment was well tolerated and showed no new safety signals.Johnson & Johnson is continuing to review the trial data, including prespecified exploratory endpoints, to determine next steps for the program, according to a statement.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0162691827.USD","CTNM","FTXH","IYH","LU0820561818.USD","LU1551013425.SGD","LU1629891620.HKD","XLV","LU2129689431.USD","LU0058720904.USD","LU1244550494.USD","LU0943347566.SGD","LU1929549753.HKD","FHLC","LU0426412945.USD","LU0820561909.HKD","LU0124676726.USD","IXJ","LU2430703251.USD","JNJ","PJP","MEDX","LU2471134952.CNY","IE00BKVL7J92.USD","VHT","LU0289739343.SGD","LU0210536198.USD","LU0882574055.USD","TRUH","LU1066051811.HKD","LU2471134879.HKD","BK4585","IE00B1BXHZ80.USD","LU2347655156.SGD","LU0466842654.USD","LU1061106388.HKD","IHE","LU0234570918.USD","GDOC","JDOC","RXL","SG9999001440.SGD","SG9999001176.USD","LU2471134523.USD","IE0001KFT4U8.USD","BK4534","IE00BLSP4452.SGD","BMED","BK4581","LU0289739699.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2667457695","title":"Medtronic PLC Stock Outperforms Competitors on Strong Trading Day","url":"https://stock-news.laohu8.com/highlight/detail?id=2667457695","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667457695?lang=en_us&edition=fundamental","pubTime":"2026-09-15 04:38","pubTimestamp":1789418280,"startTime":"0","endTime":"0","summary":"DJ Medtronic PLC Stock Outperforms Competitors On Strong Trading DayThis article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Medtronic PLC  advanced 3.12% to $93.80 Monday, on what proved to be an all-around poor trading session for the stock market, with the S&P 500 Index  falling 0.48% to 7,619.98 and Dow Jones Industrial Average  falling 0.29% to 52,421.20.The stock's rise snapped a four-day losing streak.Medtronic PLC closed 11.78% below its 52-week high of $106.33, which the company reached on November 26th.The stock outperformed some of its competitors Monday, as Johnson & Johnson  rose 0.28% to $266.32, Danaher Corp.  rose 1.55% to $203.25, and Abbott Laboratories  rose 1.12% to $103.09.Trading volume  eclipsed its 50-day average volume of 7.5 M.Data source: Dow Jones Market Data, FactSet. Data compiled September 14, 2026.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1721429402.USD","BK4568","JDOC","SG9999001440.SGD","ABT","IHI","IE000BZT7R73.USD","XLV","IE0000B7K699.USD","LU0234572021.USD","LU2456880835.USD","LU2028103732.USD","LU1935042991.SGD","MEDX","LU0109391861.USD","MDT","BK4532","LU0472753341.HKD","LU2468319806.SGD","RXL","LU2265009873.SGD","IXJ","DHR","LU2089984988.USD","LU0069063385.USD","IE0002141913.USD","PJP","FMED","LU1989764664.SGD","LU0098860793.USD","GDOC","IE00BGHQF631.EUR","BMED","FHLC","TRUH","LU0106261372.USD","IYH","IE00B42XCP33.USD","LU0203347892.USD","LU0496365809.HKD","LU2023250504.SGD","LU0053666078.USD","FTXH","TMED","IHE","JNJ","LU2111349929.HKD","LU0289961442.SGD","VHT","LU0320765489.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2667695187","title":"Contineum Therapeutics Shares Fall After Drug Trial Missed Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2667695187","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667695187?lang=en_us&edition=fundamental","pubTime":"2026-09-15 04:36","pubTimestamp":1789418160,"startTime":"0","endTime":"0","summary":"Shares of Contineum Therapeutics were trading lower after-hours Monday, following news a Phase 2 trial of an treatment for depression failed to meet its primary efficacy endpoint.Contineum said JNJ-5120/PIPE-307 is being developed by Johnson & Johnson under a global license and development agreement. The Phase 2 Moonlight-1 trial didn't meet its primary efficacy endpoint, although the treatment was well-tolerated with no new safety signals, the company added.Analyses of the data are ongoing, Contineum said.After the bell, shares of Contineum were trading 8.2% lower, at $13.59.  The stock ended the day's regular session flat, at $14.82.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PJP","JNJ","LU2430703178.SGD","SGXZ80539844.SGD","IE0009355771.USD","IE00BN8TJ469.HKD","SG9999001176.USD","GDOC","IE00BGHQF631.EUR","IYH","LU0345770308.USD","LU1551013342.USD","IE00BBT3K403.USD","LU2213496289.HKD","LU0114720955.EUR","LU0057025933.USD","LU1162221912.USD","IHE","LU1228905540.USD","FTXH","TRUH","LU0792757196.USD","LU0994945656.USD","LU2430703251.USD","MEDX","CTNM","IE0002141913.USD","LU0943347566.SGD","XLV","IE00BFTCPJ56.SGD","IE00B19Z3B42.SGD","FHLC","LU0210528500.USD","IXJ","VHT","LU0426417589.USD","LU0124676726.USD","BK4559","IE000BZT7R73.USD","JDOC","LU0203345920.USD","LU0820562030.AUD","BMED","LU0345769128.USD","LU1674673691.USD","LU0162691827.USD","RXL","BK4550","LU2456880835.USD","IE00BLSP4452.SGD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2667769302","title":"Contineum, J&J's Depression Drug Fails to Meet Mid-Stage Trial Goal","url":"https://stock-news.laohu8.com/highlight/detail?id=2667769302","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667769302?lang=en_us&edition=fundamental","pubTime":"2026-09-15 04:11","pubTimestamp":1789416676,"startTime":"0","endTime":"0","summary":"Contineum, J&J's depression drug fails to meet mid-stage trial goalSept 15 (Reuters)-Contineum TherapeuticsCTNM.Osaid on Monday an experimental depression drug it developed with Johnson & JohnsonJNJ.Nfailed to meet the main goal of a mid-stage study.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260914:nL4N4561IL:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1674673428.USD","IE000WAW04H5.SGD","LU1929549753.HKD","LU2505996509.AUD","IXJ","TRUH","LU1196500208.SGD","LU1894683348.USD","LU1629891620.HKD","CTNM","LU1430594728.SGD","LU1121112475.USD","VHT","BMED","IE00B19Z3581.USD","IE00B3T34201.USD","XLV","LU2129689605.HKD","MEDX","LU1894683264.USD","RXL","LU0820561818.USD","IE00B3PB1722.GBP","BK4559","FHLC","LU2487616109.SGD","IE0009355771.USD","JNJ","LU1074936037.SGD","LU2592432038.USD","SGXZ57979304.SGD","LU1043141123.HKD","GDOC","IE00BVYPNV92.GBP","IYH","IHE","PJP","FTXH","LU2236285917.USD","IE00BN8TJ469.HKD","IE00BDGV0183.EUR","LU0912757837.SGD","IE000M9KFDE8.USD","LU2213496289.HKD","LU0234572021.USD","IE00BZ1G4Q59.USD","LU2133065610.SGD","LU2023250330.USD","JDOC","LU0345769631.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2667693701","title":"Contineum Therapeutics, - Johnson & Johnson Continues to Evaluate Trial Data for Jnj-5120/Pipe-307","url":"https://stock-news.laohu8.com/highlight/detail?id=2667693701","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667693701?lang=en_us&edition=fundamental","pubTime":"2026-09-15 04:05","pubTimestamp":1789416300,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260914:nTUABTMJR3:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["MEDX","LU0994945656.USD","LU2468319806.SGD","RXL","CTNM","LU0345769128.USD","LU0545562505.USD","JDOC","FHLC","LU1989771016.USD","LU0072461881.USD","IHE","LU1929549753.HKD","FTXH","LU1674673428.USD","PJP","LU0345770993.USD","GDOC","IE00B42XCP33.USD","IYH","LU1043141123.HKD","LU1145028129.USD","LU0882574055.USD","LU0432979614.USD","LU2456880835.USD","LU0053666078.USD","IE0002141913.USD","XLV","JNJ","LU1674673691.USD","LU0234572021.USD","VHT","IE000BZT7R73.USD","LU1496350502.SGD","LU1935042991.SGD","LU0210536198.USD","IE00BGHQF631.EUR","BK4533","LU0098860793.USD","TRUH","LU0820562030.AUD","BMED","SG9999001440.SGD","LU0289961442.SGD","LU0203347892.USD","LU1043141396.HKD","LU1066051498.USD","LU0792757196.USD","IXJ","IE0001KFT4U8.USD"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2667970669","title":"Sector Update: Healthcare Stocks Rise Premarket Monday","url":"https://stock-news.laohu8.com/highlight/detail?id=2667970669","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667970669?lang=en_us&edition=fundamental","pubTime":"2026-09-14 21:17","pubTimestamp":1789391865,"startTime":"0","endTime":"0","summary":"Healthcare stocks were rising premarket Monday, with the State Street Health Care Select Sector SPDR ETF  advancing by 1.2% and the iShares Biotechnology ETF  0.3% higher.GSK  licensor Hansoh Pharmaceutical reported that a phase 3 trial evaluating risvutatug rezetecan, or Ris-Rez, against commonly used topotecan in patients with relapsed small-cell lung cancer met its primary endpoint. GSK stock was up more than 4% pre-bell.Astrazeneca  shares were up more than 2% after the company said a late-stage study of its drug Enhertu showed a six-month improvement in median progression-free survival as a first-line treatment for advanced HER2-mutant non-small cell lung cancer.Johnson & Johnson  stock was up more than 1% after the company said a phase 3 trial of its lung cancer drug Rybrevant combined with chemotherapy resulted in a median overall survival of 34.3 months. Separately, The Wall Street Journal reported that Apollo Global Management  is in talks to acquire Johnson & Johnson's 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Chatter: Apollo Global in Talks to Buy J&J Orthopedics Unit for $20 Billion","url":"https://stock-news.laohu8.com/highlight/detail?id=2667654231","media":"MT Newswires Live","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667654231?lang=en_us&edition=fundamental","pubTime":"2026-09-14 17:35","pubTimestamp":1789378500,"startTime":"0","endTime":"0","summary":"Apollo Global Management  is in talks to acquire Johnson & Johnson's  hips-and-knees business for about $20 billion, The Wall Street Journal reported Saturday, citing unnamed people familiar with the matter.The report said J&J has been seeking to separate its DePuy Synthes orthopedics unit, which generated $9.3 billion in sales last year.The talks with Apollo may not result in a deal, and other bidders could emerge, the report said.Apollo and J&J did not immediately respond MT Newswires' request for 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& Johnson Says Lung Cancer Drug Combination Extends Median Survival to Over 34 Months","url":"https://stock-news.laohu8.com/highlight/detail?id=2667373659","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2667373659?lang=en_us&edition=fundamental","pubTime":"2026-09-14 16:20","pubTimestamp":1789374055,"startTime":"0","endTime":"0","summary":"Johnson & Johnson  said Sunday a Phase 3 trial of its lung cancer drug Rybrevant combined with chemotherapy resulted in a median overall survival of 34.3 months.The treatment combination extended patient survival by more than six months compared to the 27.9-month median observed in the standalone chemotherapy group, the company said.An analysis adjusting for trial participants who switched to the experimental therapy after their disease progressed demonstrated a 43% lower risk of death, it said.The most common side effects from the treatment included paronychia, neutropenia, and rash, Johnson & 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Altman even suggested OpenAI may delay its 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