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Septerna, Inc.

36.90

+0.90002.50%

Volume:745.39K

Turnover:26.89M

Market Cap:1.72B

PE:-68.03

High:37.09

Open:35.47

Low:34.66

Close:36.00

52wk High:51.10

52wk Low:17.55

Shares:46.68M

Float Shares:22.90M

Volume Ratio:1.37

T/O Rate:3.26%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-0.5424

EPS(LYR):-1.1044

ROE:-6.34%

ROA:-7.13%

PB:4.45

PE(LYR):-33.41

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Overview Company News Filings

Septerna is Maintained at Buy by Guggenheim

Septerna price target raised to $49 from $45 at Raymond James

C4 Therapeutics Q2 Revenue Beats Estimates, Helped by Roche Collaboration

Septerna Q2 Loss Narrows, Revenue Rises

MT Newswires Live

Septerna, Inc. Reports Results for the Quarter Ended June 30 - Earnings Summary

Earnings Flash (SEPN) Septerna Posts Q2 Loss Per Share $0.29, vs. FactSet Est of $0.43 Loss

MT Newswires Live

Septerna Q2 Revenue Beats Analyst Estimates, Driven by Novo Nordisk Partnership

Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate

Benzinga Earnings

Press Release: Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results

Septerna SVP Drug Discovery Daniel D. Long Sells USD 114,901.29 in Common Shares

3 Small-Cap Stocks Analysts Expect to Rally Big

3 Small-Cap Stocks with ‘Strong Buy’ Ratings and 40%+ Upside, According to Analysts

Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974

Is Septerna (SEPN) Fully Valued Following Its Russell Index Inclusions?

Simply Wall St.

Septerna SVP Drug Discovery Daniel D. Long Disposes of 3,333 Common Shares Worth $113,104.20

Truist Securities Adjusts Septerna Price Target to $43 From $35, Maintains Buy Rating

MT Newswires Live

Septerna Price Target Maintained with a $40.00/share by HC Wainwright & Co.

Septerna is Maintained at Buy by Truist Securities

Septerna price target raised to $43 from $35 at Truist

Analysts Offer Insights on Technology Companies: Septerna, Inc. (SEPN) and Strategy (MSTR)

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The firm updated its m...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/septerna-price-target-raised-to-49-from-45-at-raymond-james-thefly-news?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/septerna-price-target-raised-to-49-from-45-at-raymond-james-thefly-news?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["RJF","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658992565","title":"C4 Therapeutics Q2 Revenue Beats Estimates, Helped by Roche Collaboration","url":"https://stock-news.laohu8.com/highlight/detail?id=2658992565","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658992565?lang=en_us&edition=fundamental","pubTime":"2026-08-11 19:08","pubTimestamp":1786446516,"startTime":"0","endTime":"0","summary":"C4 Therapeutics Q2 revenue beats estimates, helped by Roche collaborationOverviewUS biopharma firm's Q2 revenue rose slightly, beating analyst expectationsQ2 net loss per share was $0.18, better than ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260811:nL1N4480D3:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","CCCC","BK4585","SEPN","BK4505","BK4139","BK4007","BBIO"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658795134","title":"Septerna Q2 Loss Narrows, Revenue Rises","url":"https://stock-news.laohu8.com/highlight/detail?id=2658795134","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658795134?lang=en_us&edition=fundamental","pubTime":"2026-08-11 04:26","pubTimestamp":1786393576,"startTime":"0","endTime":"0","summary":"Septerna (SEPN) reported Q2 loss late Monday of $0.29 per diluted share, narrower from $0.56 a year earlier.Analysts polled by FactSet expected a loss of $0.43.Revenue for the quarter ended June 30 was $26.7 million, up from $119,000 a year earlier.Analysts expected $19.2 million.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658959255","title":"Septerna, Inc. 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This is a 48.21 percent increase over losses of $(0.56) per share from the","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/26/08/61091200/septerna-q2-eps-0-29-beats-0-43-estimate-sales-26-746m-beat-17-875m-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":"Septerna Q2 EPS $(0.29) Beats $(0.43) Estimate, Sales $26.746M Beat $17.875M Estimate","news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2658411956","title":"Press Release: Septerna Highlights Business Progress and Reports Second Quarter 2026 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2658411956","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658411956?lang=en_us&edition=fundamental","pubTime":"2026-08-11 04:01","pubTimestamp":1786392060,"startTime":"0","endTime":"0","summary":"-- Septerna's Phase 1 clinical trial of SEP-479, a potent, selective. oral small molecule PTH1R agonist for the treatment of. serum calcium and endogenous serum PTH) in healthy volunteers.-- Based on pharmacokinetic data from the ongoing Phase 1 clinical. trial, the observed elimination half-life of SEP-479 is. approximately three to four days, which the Company anticipates. will support once-daily dosing. To fully characterize steady-state. pharmacokinetics, dosing for the MAD cohorts will be extended to. 14 days. As a result, Septerna expects to report Phase 1 data from. both the SAD and MAD cohorts in the first quarter of 2027.-- During the quarter, the Company presented the first detailed. preclinical characterization of SEP-479 in an oral presentation at. ENDO 2026, highlighting data supporting its potential as a. -- As reported in March 2026, SEP-631, an oral small molecule MRGPRX2","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4097","BK4232","BK4599","PRGS","R","BK4022","GPCR","LU2065732104.USD","BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2657572937","title":"Septerna SVP Drug Discovery Daniel D. Long Sells USD 114,901.29 in Common Shares","url":"https://stock-news.laohu8.com/highlight/detail?id=2657572937","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2657572937?lang=en_us&edition=fundamental","pubTime":"2026-08-06 07:17","pubTimestamp":1785971827,"startTime":"0","endTime":"0","summary":"Septerna SVP Drug Discovery Daniel D. Long sells USD 114,901.29 in common sharesSepterna SVP, Drug Discovery Daniel D. Long sold 3,334 shares on Aug. 3 under a 10b5-1 plan.Sales priced at USD 33.98 an","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260805:nNDL7Mtvbt:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna SVP Drug Discovery Daniel D. 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($SEPN), Kornit Digit...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/3-small-cap-stocks-analysts-expect-to-rally-big?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/3-small-cap-stocks-analysts-expect-to-rally-big?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2652211586","title":"3 Small-Cap Stocks with ‘Strong Buy’ Ratings and 40%+ Upside, According to Analysts","url":"https://stock-news.laohu8.com/highlight/detail?id=2652211586","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2652211586?lang=en_us&edition=fundamental","pubTime":"2026-07-20 22:15","pubTimestamp":1784556959,"startTime":"0","endTime":"0","summary":"Small-cap stocks often go unnoticed, but a few are grabbing Wall Street’s attention. Analysts are highlighting Septerna, Inc. ($SEPN), Kornit Digit...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/3-small-cap-stocks-with-strong-buy-ratings-and-big-upside-according-to-analysts?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/3-small-cap-stocks-with-strong-buy-ratings-and-big-upside-according-to-analysts?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2652337002","title":"Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974","url":"https://stock-news.laohu8.com/highlight/detail?id=2652337002","media":"Reuters","labels":["shareholding","insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2652337002?lang=en_us&edition=fundamental","pubTime":"2026-07-18 07:01","pubTimestamp":1784329288,"startTime":"0","endTime":"0","summary":"Septerna President and COO Elizabeth Bhatt sells 4,000 shares for $135,974Septerna President and COO Elizabeth Bhatt sold 4,000 shares on July 15 at USD 33.99.She exercised stock options for 4,000 sha","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260717:nNDL633WXk:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Septerna President and COO Elizabeth Bhatt Sells 4,000 Shares for $135,974","news_tag":"shareholding,insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2650615176","title":"Is Septerna (SEPN) Fully Valued Following Its Russell Index Inclusions?","url":"https://stock-news.laohu8.com/highlight/detail?id=2650615176","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2650615176?lang=en_us&edition=fundamental","pubTime":"2026-07-11 23:28","pubTimestamp":1783783710,"startTime":"0","endTime":"0","summary":"Septerna (SEPN) recently joined several Russell growth and small cap indices. This change can affect how index-tracking and benchmark-aware funds treat the stock and influence overall investor attention.\nSee our latest analysis for Septerna.\nSepterna’s recent Russell index inclusions come after a strong run in the stock, with a 90 day share price return of 55.61% and a 1 year total shareholder return of 206.31%. This comes even though the latest close at $35.93 followed a 1 day share price...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-fully-valued-following-its-russell-index-in","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-sepn/septerna/news/is-septerna-sepn-fully-valued-following-its-russell-index-in","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648639940","title":"Septerna SVP Drug Discovery Daniel D. Long Disposes of 3,333 Common Shares Worth $113,104.20","url":"https://stock-news.laohu8.com/highlight/detail?id=2648639940","media":"Reuters","labels":["insiderTrades"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648639940?lang=en_us&edition=fundamental","pubTime":"2026-07-03 07:00","pubTimestamp":1783033255,"startTime":"0","endTime":"0","summary":"Septerna SVP Drug Discovery Daniel D. Long disposes of 3,333 common shares worth $113,104.20Septerna SVP, Drug Discovery Daniel D. Long exercised stock options for 3,333 shares at USD 2.76 on July 1, ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260702:nNDL3WRqJz:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Septerna SVP Drug Discovery Daniel D. Long Disposes of 3,333 Common Shares Worth $113,104.20","news_tag":"insiderTrades","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN","BK4007"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648543459","title":"Truist Securities Adjusts Septerna Price Target to $43 From $35, Maintains Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2648543459","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648543459?lang=en_us&edition=fundamental","pubTime":"2026-07-01 20:46","pubTimestamp":1782909983,"startTime":"0","endTime":"0","summary":"Truist Securities Adjusts Septerna Price Target to $43 From $35, Maintains Buy Rating","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648480125","title":"Septerna Price Target Maintained with a $40.00/share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2648480125","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648480125?lang=en_us&edition=fundamental","pubTime":"2026-07-01 20:29","pubTimestamp":1782908940,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SEPN/analyst-ratings(END) Dow Jones NewswiresJuly 01, 2026 08:29 ET","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648483455","title":"Septerna is Maintained at Buy by Truist Securities","url":"https://stock-news.laohu8.com/highlight/detail?id=2648483455","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648483455?lang=en_us&edition=fundamental","pubTime":"2026-07-01 20:03","pubTimestamp":1782907380,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/SEPN/analyst-ratings(END) Dow Jones NewswiresJuly 01, 2026 08:03 ET","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SEPN"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2648517241","title":"Septerna price target raised to $43 from $35 at Truist","url":"https://stock-news.laohu8.com/highlight/detail?id=2648517241","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2648517241?lang=en_us&edition=fundamental","pubTime":"2026-07-01 19:20","pubTimestamp":1782904848,"startTime":"0","endTime":"0","summary":"Truist analyst Srikripa Devarakonda raised the firm’s price target on Septerna (SEPN) to $43 from $35 and keeps a Buy rating on the shares. 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